Concepedia

Publication | Open Access

Aldose Reductase Protects Against Early Atherosclerotic Lesion Formation in Apolipoprotein E-Null Mice

DOIFull Paper Access

72

Citations

31

References

2009

Year

Sanjay Srivastava, Elena Vladykovskaya, Oleg A. Barski, Matthew Spite, Karin Kaiserová, J. Mark Petrash, Stephen S.M. Chung, Greg Hunt, Buddhadeb Dawn, Aruni Bhatnagar
Circulation Research

Abstract

These observations indicate that AR is upregulated in atherosclerotic lesions and it protects against early stages of atherogenesis by removing toxic aldehydes generated in oxidized lipids.

References

YearCitations

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