Polymorphism in ftsI gene and -lactam susceptibility in Portuguese Haemophilus influenzae strains: clonal dissemination of -lactamase-positive isolates with decreased susceptibility to amoxicillin/clavulanic acid

Abstract

This study shows that the non-enzymatic mechanism of resistance to β-lactams is widespread among H. influenzae isolates in Portugal. Clonal dissemination of BLPACR strains showing high resistance to ampicillin and reduced susceptibility to amoxicillin/clavulanic acid was documented.