PHARMACOKINETICS OF CITALOPRAM IN RELATION TO GENETIC POLYMORPHISM OF CYP2C19

The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans.

S.M. de Morais, G. Wilkinson, Joyce Blaisdell et al. · Journal of Biological Chemistry · 1994 · 952 citations · Full text

Identification of a new genetic defect responsible for the polymorphism of (S)-mephenytoin metabolism in Japanese.

Sara Moráis, G. Wilkinson, Joyce Blaisdell et al. · Molecular Pharmacology · 1994 · 750 citations

Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin

Leif Bertilsson, Ya‐Qing Lou, Yun-Long Du et al. · Clinical Pharmacology & Therapeutics · 1992 · 403 citations

Biology, Pronounced Differences, Chinese Subjects +15

Pharmacogenetics of mephenytoin: A new drug hydroxylation polymorphism in man

A. K�pfer, R Preisig · European Journal of Clinical Pharmacology · 1984 · 363 citations

Pharmacology, Pharmacogenomics, Medicine

Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450. Studies in rats and patients.

Paul B. Watkins, Scott A Murray, L G Winkelman et al. · Journal of Clinical Investigation · 1989 · 351 citations · Full text

Pharmacotherapy, Experimental Pharmacology, Physiologically-based Pharmacokinetic Modeling +20