Synthetically Accessible Non-Secosteroidal Hybrid Molecules Combining Vitamin D Receptor Agonism and Histone Deacetylase Inhibition

Cutting Edge: 1,25-Dihydroxyvitamin D3 Is a Direct Inducer of Antimicrobial Peptide Gene Expression

Tiantian Wang, Frederick P. Nestel, Véronique Bourdeau et al. · The Journal of Immunology · 2004 · 1.6K citations · Full text

Substrate and Functional Diversity of Lysine Acetylation Revealed by a Proteomics Survey

Sung Chan Kim, Robert W. Sprung, Yue Chen et al. · Molecular Cell · 2006 · 1.5K citations · Full text

Protein Chemistry, Biochemistry, Functional Diversity +9

Highly enantioselective borane reduction of ketones catalyzed by chiral oxazaborolidines. Mechanism and synthetic implications

E. J. Corey, Raman K. Bakshi, Saizo Shibata · Journal of the American Chemical Society · 1987 · 1.4K citations

Chemical Engineering, Engineering, Synthetic Implications +13

A stable and easily prepared catalyst for the enantioselective reduction of ketones. Applications to multistep syntheses

E. J. Corey, Raman K. Bakshi, Saizo Shibata et al. · Journal of the American Chemical Society · 1987 · 863 citations

Chemical Engineering, Enantioselective Reduction, Engineering +11

A Fluorogenic Histone Deacetylase Assay Well Suited for High-Throughput Activity Screening

Dennis Wegener, Frank Wirsching, Daniel Riester et al. · Chemistry & Biology · 2003 · 272 citations · Full text

Histone Modifications, Chromatin, High-throughput Activity Screening +12