Gold(I)‐Catalyzed 5‐<i>endo</i> Hydroxy‐ and Alkoxycyclization of 1,5‐Enynes: Efficient Access to Functionalized Cyclopentenes

Abstract

The rapid and stereoselective construction of highly functionalized cyclopentenes is possible through gold(I)-catalyzed 5-endo hydroxy- and methoxycyclizations of 1,5-enynes. More complex 5,7- and 5,8-fused bicyclic structures of a type found in many terpene natural products can be formed by combining the cyclization reaction with ring-closing metathesis (RCM; see scheme). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2007/z604140_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.