Concepedia

Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development

T. Matsuyama, Tohru Kimura, Motoo Kitagawa, Klaus Pfeffer, Takatoshi Kawakami, Nobumasa Watanabe, Thomas M. Kündig, Ryuichi Amakawa, Kenji Kishihara, Andrew Wakeham,

Cell · 1993 · 643 citations · 65 references

DOI

Concepts

References

65

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

Kirk R. Thomas, Mario R. Capecchi · Cell · 1987 · 2.4K citations

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The <i>in vitro</i> development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

Thomas Doetschman, Harald Eistetter, Margot Katz et al. · Development · 1985 · 2K citations

, , +17

Ablation of “tolerance” and induction of diabetes by virus infection in viral antigen transgenic mice

Pamela S. Ohashi, Stephan Oehen, Kurt Buerki et al. · Cell · 1991 · 1.2K citations

, , +15

Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-β gene regulatory elements

Masaaki Miyamoto, Takashi Fujita, Yoko Kimura et al. · Cell · 1988 · 1K citations

, , +12

Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development

Michael A. Rudnicki, Thomas Braun, Shuji Hinuma et al. · Cell · 1992 · 988 citations

, , +10