1,2‐Dicarbonyl Compounds as Pronucleophiles in Organocatalytic Asymmetric Transformations

Abstract

Organocatalysis likes them too! 1,2-dicarbonyl compounds possess high synthetic potential because of their adjacent multiple reactive centers. Recent contributions indicate that these reactive species, with an appropriate activation mode, may also act as efficient pronucleophiles in asymmetric organocatalyzed sequential or domino transformations including CC or CN bond formation (see scheme).