Convenient RCM-Mediated Synthesis and Spectroscopic Study of Novel Ferrocenyl-Substituted 2,5,8,9-Tetrahydro-3H-imidazo[1,2-a][1,3]diazepin-3-ones

Abstract

The ferrocene-containing N-BOC-protected 1-allyl-2-(allylamino)imidazolones 5 and 13 were transformed into mono- and bis(2,5,8,9-tetrahydro-3H-imidazo[1,2-a][1,3]diazepin-3-ones) 7 and 15 in a ring-closing metathesis (RCM) reaction using Grubbs’ catalyst [RuCl2(CHPh){P(cyclo-C6H11)3}2]. The structures of the novel compounds were identified by IR and multinuclear NMR spectroscopy. (© Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002)