Platelet and Neutrophil Responses to Gram Positive Pathogens in Patients with Bacteremic Infection

Abstract

We have demonstrated for the first time that bacteria isolated from patients with Gram-positive bacteremia can induce platelet activation and aggregation, PNC formation, and neutrophil activation in the same infected host. This underlines the significance of these interactions during infection, which could be a target for future therapies in sepsis.