Concepedia

Protective effect of the immunomodulator AS101 against cyclophosphamide-induced testicular damage in mice

A. Carmely, Dror Meirow, Avi Peretz, Michael Albeck, B. Bartoov, Benjamin Sredni

Human Reproduction · 2009 · 69 citations · 30 references

DOI

Abstract

Our results indicate that AS101 can significantly protect against Cy-induced testicular damage and sperm DNA damage, probably by acting through Akt/GSK-3beta phosphorylation.

References

30

A Simple Method for the Analysis of Clustered Binary Data

J. N. K. Rao, A. J. Scott · Biometrics · 1992 · 686 citations

, , +24

Akt mediates self-renewal division of mouse spermatogonial stem cells

Jiyoung Lee, Mito Kanatsu-Shinohara, Kimiko Inoue et al. · Development · 2007 · 263 citations

, , +14

Subclinical depletion of primordial follicular reserve in mice treated with cyclophosphamide: clinical importance and proposed accurate investigative tool

Dror Meirow, David Nugent, M. Epstein · Human Reproduction · 1999 · 262 citations · Full text

Inhibition of Phosphatidylinositol-3-OH Kinase/Akt Signaling Impairs DNA Repair in Glioblastoma Cells following Ionizing Radiation

Gary D. Kao, Zibin Jiang, A. Fernandes et al. · Journal of Biological Chemistry · 2007 · 229 citations · Full text

Sperm aneuploidy frequencies analysed before and after chemotherapy in testicular cancer and Hodgkin's lymphoma patients

Helen G. Tempest, Edmund Ko, Peter Chan et al. · Human Reproduction · 2007 · 195 citations · Full text