Proliferation and hypoxia in human squamous cell carcinoma of the cervix: First report of combined immunohistochemical assays

Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy

Robert A. Gatenby, Howard Kessler, Jay S. Rosenblum et al. · International Journal of Radiation Oncology*Biology*Physics · 1988 · 805 citations

Medicine, Oncology, Radiation Oncology +16

Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.

Thomas G. Graeber, Jeff Peterson, Mitchell H. Tsai et al. · Molecular and Cellular Biology · 1994 · 614 citations · Full text

Medicine, Genetics, Oncology +13

New Ki-67-equivalent murine monoclonal antibodies (MIB 1-3) generated against bacterially expressed parts of the Ki-67 cDNA containing three 62 base pair repetitive elements encoding for the Ki-67 epitope.

Göran Key, Michael Becker, Byron Baron et al. · PubMed · 1993 · 382 citations

Pharmacy, Molecular Biology, Molecular Genetics +13

Noninvasive measurement of interstitial pH profiles in normal and neoplastic tissue using fluorescence ratio imaging microscopy.

Gaelle Martin, R K Jain · PubMed · 1994 · 311 citations

Medicine, Biomedical Engineering, Oncology +17

Evidence that hypoxia markers detect oxygen gradients in liver: pimonidazole and retrograde perfusion of rat liver

RG Thurman, J.M. Yates, JA Raleigh · British Journal of Cancer · 1995 · 297 citations · Full text

Life Sciences, Pharmacology, Physiology +13