Evaluation of PTEN and Mcl-1 expressions in NSCLC expressing wild-type or mutated EGFR

Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib

Thomas J. Lynch, Daphne W. Bell, Raffaella Sordella et al. · New England Journal of Medicine · 2004 · 11.5K citations

Medicine, Oncology, Pharmacology +16

<i>EGFR</i> Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy

J. Guillermo Paez, Pasi A. Jänne, Jeffrey C. Lee et al. · Science · 2004 · 9.4K citations

Medicine, Molecular Genetics, Oncology +17

EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinib

William Pao, Vincent A. Miller, Maureen F. Zakowski et al. · Proceedings of the National Academy of Sciences · 2004 · 4.3K citations · Full text

Medicine, Molecular Genetics, Oncology +16

Aberrant Epidermal Growth Factor Receptor Signaling and Enhanced Sensitivity to EGFR Inhibitors in Lung Cancer

Joseph M. Amann, Shailaja Kalyankrishna, Pierre P. Massion et al. · Cancer Research · 2005 · 436 citations · Full text

Medicine, Oncology, Pharmacology +17

Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation.

Jean‐Charles Soria, Ho‐Young Lee, Janet I. Lee et al. · PubMed · 2002 · 409 citations

Medicine, Genetics, Oncology +17