Second-generation organocatalysts for the highly enantioselective dynamic kinetic resolution of azlactones

Albrecht Berkessel, Santanu Mukherjee, Felix Cleemann, Thomas N. Müller, Johann Lex

Chemical Communications · 2005 · 141 citations · 13 references

Concepts

Abstract

Bifunctional organocatalysts of the thiourea-tert-amine type, carrying two "matched" elements of chirality, effect the alcoholytic dynamic kinetic resolution of a variety of azlactones with up to 95% ee.

References

13