Intracranial Self-Stimulation in Rats: Sensitization to an Opioid Antagonist Following Acute or Chronic Treatment with Mu Opioid Agonists,

A psychomotor stimulant theory of addiction.

Roy A. Wise, Michael A. Bozarth · Psychological Review · 1987 · 2.7K citations

Medicine, Neuroscience, Pharmacology +17

Goodman and Gilman's The Pharmacological Basis of Therapeutics

Robert C. Hastings, Gillis W. Long · JAMA · 1991 · 1.1K citations

Medicine, Pharmacology, Pharmacotherapy +6

U-50,488: a selective and structurally novel non-Mu (kappa) opioid agonist.

Philip F. VonVoigtlander, Robert A. Lahti, James H. Ludens · Journal of Pharmacology and Experimental Therapeutics · 1983 · 816 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Role of different brain structures in the expression of the physical morphine withdrawal syndrome.

Rafaël Maldonado, Luis Stinus, Lisa Gold et al. · Journal of Pharmacology and Experimental Therapeutics · 1992 · 389 citations

Medicine, Neuroscience, Pharmacology +17

Nucleus accumbens and amygdala are possible substrates for the aversive stimulus effects of opiate withdrawal

Luis Stinus, Michel Le Moal, George F. Koob · Neuroscience · 1990 · 318 citations

Nursing, Neurobiology, Neuroscience +13