2009 · 163 citations · 19 references
Life SciencesBioinformaticsSystems BiologyAlgorithmsComputational BiologyDistributed SystemsDistributed ComputingNetwork AlignmentNetwork OptimizationAlignment ProblemBelief PropagationBiological Network AlignmentComputational Alignment AlgorithmsGraph MatchingMatchingOntology Matching
We propose a new distributed algorithm for sparse variants of the network alignment problem, which occurs in a variety of data mining areas including systems biology, database matching, and computer vision. Our algorithm uses a belief propagation heuristic and provides near optimal solutions for this NP-hard combinatorial optimization problem. We show that our algorithm is faster and outperforms or ties existing algorithms on synthetic problems, a problem in bioinformatics, and a problem in ontology matching. We also provide a unified framework for studying and comparing all network alignment solvers.
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