Practical Syntheses of (2<i>S</i>)‐R207910 and (2<i>R</i>)‐R207910

S. Chandrasekhar, G. Babu, Debendra K. Mohapatra

European Journal of Organic Chemistry · 2011 · 33 citations · 20 references

Concepts

Abstract

Abstract Concise and practical syntheses of (2 S )‐R207910 ( 3a ) and (2 R )‐R207910 ( 3b ) have been achieved in high overall yield of 12 % in 10 steps for each isomer starting from a known intermediate following Sharpless asymmetric epoxidation, regioselective epoxide opening, modified allylzinc bromide addition as key reactions.

References

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