Receptor tyrosine kinase AXL is induced by chemotherapy drugs and overexpression of AXL confers drug resistance in acute myeloid leukemia

Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note.

Scott H. Kaufmann · PubMed · 1989 · 934 citations

Life Sciences, Cell Biology, Molecular Biology +16

Criteria for the Diagnosis of Acute Leukemia of Megakaryocyte Lineage (M7)

John M. Bennett · Annals of Internal Medicine · 1985 · 741 citations

Medicine, Hematology, Oncology +17

axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase.

John P. O’Bryan, Roy A. Frye, Patricia C. Cogswell et al. · Molecular and Cellular Biology · 1991 · 723 citations · Full text

Medicine, Molecular Biology, Molecular Genetics +13

Gene-Expression Patterns in Drug-Resistant Acute Lymphoblastic Leukemia Cells and Response to Treatment

Amy de Haar-Holleman, Meyling Cheok, Monique L. den Boer et al. · New England Journal of Medicine · 2004 · 644 citations · Full text

Medicine, Oncology, Pharmacology +14

The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade.

Guidalberto Manfioletti, Claudio Brancolini, Gian Carlo Avanzi et al. · Molecular and Cellular Biology · 1993 · 590 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +8