SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251.6K citations

Life Sciences, Microbiology, Molecular Biology +14

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

Frank C. Arnett, Steven M. Edworthy, D. Blöch et al. · Arthritis & Rheumatism · 1988 · 19.9K citations

Medicine, Clinical Sciences, Internal Medicine +12

Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase

Anne Brunet, Lora B. Sweeney, James Fitzhugh Sturgill et al. · Science · 2004 · 3.2K citations

Life Sciences, Biochemistry, Molecular Biology +15

Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase

Fan Yeung, Jamie E. Hoberg, C S Ramsey et al. · The EMBO Journal · 2004 · 2.7K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +16

hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase

Homayoun Vaziri, Scott Dessain, Elinor Ng Eaton et al. · Cell · 2001 · 2.6K citations · Full text

Life Sciences, Genetics, Molecular Biology +8