Development of a Lectin Microarray for the Rapid Analysis of Protein Glycopatterns

Abstract

Glycosylation plays a role in a wide variety of biological processes including bacterial pathogenesis, tumor cell metastasis and inflammation. Despite the importance of carbohydrates, few techniques exist for the rapid and systematic evaluation of protein glycosylation. This paper describes a lectin microarray for the rapid analysis of protein glycopatterns (see scheme). Supporting information for this article is available on the WWW under http://www.chembiochem.org or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.