The effects of lidocaine on intracellular and extracellular potentials, activation, and ventricular arrhythmias during acute regional ischemia in the isolated porcine heart.

The effect of acute coronary artery occlusion on subepicardial transmembrane potentials in the intact porcine heart.

Eugene Downar, M J Janse, D Durrer · Circulation · 1977 · 450 citations

Medicine, Cardiology, Physiology +17

Mechanism and time course of S-T and T-Q segment changes during acute regional myocardial ischemia in the pig heart determined by extracellular and intracellular recordings.

André G. Kléber, Michiel J. Janse, F J van Capelle et al. · Circulation Research · 1978 · 415 citations

Medicine, Cardiology, Physiology +13

Accumulation of lysophosphoglycerides with arrhythmogenic properties in ischemic myocardium.

Sobel Be, Peter B. Corr, Alice K. Robison et al. · Journal of Clinical Investigation · 1978 · 300 citations · Full text

Medicine, Cardiology, Physiology +17

Effect of lidocaine on the electrophysiological properties of ventricular muscle and Purkinje fibers

J. Thomas Bigger, William J. Mandel · Journal of Clinical Investigation · 1970 · 269 citations · Full text

Medicine, Pharmacology, Physiology +17

Lidocaine disposition kinetics in monkey and man; I. Prediction by a perfusion model

Neal L. Benowitz, Ralph P. Forsyth, Kenneth L. Melmon et al. · Clinical Pharmacology & Therapeutics · 1974 · 213 citations

Pharmacy, Pharmacokinetics, Physiology +15