Concepedia

New aryloxy-quinone derivatives as potential anti-Chagasic agents: synthesis, trypanosomicidal activity, electrochemical properties, pharmacophore elucidation and 3D-QSAR analysis

Karina Vázquez, Christian Espinosa‐Bustos, Jorge Soto‐Delgado, Ricardo A. Tapia, Javier Varela, Estefanía Birriel, Rodrigo Segura, Jaime Pizarro, Hugo Cerecetto, Mercedes González,

RSC Advances · 2015 · 32 citations · 35 references

DOI

Concepts

Abstract

A set of new aryloxy-quinones were synthesized and evaluated<italic>in vitro</italic>against the epimastigote form of<italic>Trypanosoma cruzi</italic>and their unspecific cytotoxicity was tested on murine macrophages J-774 cells.

References

35

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Towards a Paradigm Shift in the Treatment of Chronic Chagas Disease

Rodolfo Viotti, Belkisyolé Alarcón de Noya, Tânia Cremonini de Araújo-Jorge et al. · Antimicrobial Agents and Chemotherapy · 2013 · 234 citations · Full text

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Open3DQSAR: a new open-source software aimed at high-throughput chemometric analysis of molecular interaction fields

Paolo Tosco, Thomas Balle · Journal of Molecular Modeling · 2010 · 172 citations

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Schiff bases of indoline-2,3-dione (isatin) derivatives and nalidixic acid carbohydrazide, synthesis, antitubercular activity and pharmacophoric model building

Tarek Aboul‐Fadl, Fayzah A. S. Bin-Jubair, Omima Aboul-Wafa · European Journal of Medicinal Chemistry · 2010 · 168 citations

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Some Applications of Electrochemistry in Biomedical Chemistry. Emphasis on the Correlation of Electrochemical and Bioactive Properties

Fabiane C. de Abreu, Patrícia A. de L. Ferraz, Marília Oliveira Fonseca Goulart · Journal of the Brazilian Chemical Society · 2002 · 144 citations · Full text

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