Bioinformatics · 2015 · 1.1K citations · 2 references
Life SciencesBioinformaticsVisualizationInformation VisualizationScientific VisualizationSequence AnalysisProtein Sequence AnalysisSequence AnnotationSequence VisualizationProtein Sequence VisualizationSequence Diagrams
Biological sequence diagrams are fundamental for visualizing functional elements in protein or nucleotide sequences, enabling summarization, presentation, and intuitive discovery of new insights. This study introduces IBS, a software package that represents protein or nucleotide sequence organization in a convenient, efficient, and precise manner. IBS offers multiple options for manipulating, recoloring, and rescaling sequences in a user‑defined mode, and its artwork can be exported as publication‑quality figures. IBS is freely available as a standalone Java package and an online HTML5/JavaScript service at http://ibs.biocuckoo.org. Contact authors at renjian.sysu@gmail.com or xueyu@hust.edu.cn; supplementary data are available online.
Abstract Summary: Biological sequence diagrams are fundamental for visualizing various functional elements in protein or nucleotide sequences that enable a summarization and presentation of existing information as well as means of intuitive new discoveries. Here, we present a software package called illustrator of biological sequences (IBS) that can be used for representing the organization of either protein or nucleotide sequences in a convenient, efficient and precise manner. Multiple options are provided in IBS, and biological sequences can be manipulated, recolored or rescaled in a user-defined mode. Also, the final representational artwork can be directly exported into a publication-quality figure. Availability and implementation: The standalone package of IBS was implemented in JAVA, while the online service was implemented in HTML5 and JavaScript. Both the standalone package and online service are freely available at http://ibs.biocuckoo.org. Contact: renjian.sysu@gmail.com or xueyu@hust.edu.cn Supplementary information: Supplementary data are available at Bioinformatics online.
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