ANALYSIS OF 5-HYDROXYTRYPTAMINE 2C RECEPTOR GENE PROMOTER VARIANTS AS ALCOHOL-DEPENDENCE RISK FACTORS

Abstract

Although we report a lack of association between alcohol dependence and five common promoter polymorphisms, and the constituted haplotypes, the analysis tends to indicate gender and sub-type differences. We suggest that a follow up study with larger sample numbers should be performed to improve the power to detect the genetic influences of HTR2C in alcohol dependence.