Chiral Polyesters by Dynamic Kinetic Resolution Polymerization

Abstract

Problem resolved: Enzymatic polymerization was combined with an in situ Ru-catalyzed racemization process. The reaction mixture comprises a racemic mixture of a chiral diol and dimethyl adipate. Because of the high stereoselectivity of the enzyme Candida antarctica lipase B (CALB), the S-configured stereocenters of the chiral diol are practically nonreactive. Polycondensation was achieved by concurrent racemization of the S- into the R-configured centers. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2006/z503496_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.