Patterning Solid-Supported Lipid Bilayer Membranes by Lithographic Polymerization of a Diacetylene Lipid

Abstract

Micropatterned lipid bilayers have been created on solid supports by using lithographic polymerization of a diacetylene lipid (see picture). The domains of polymerized (light) serve, after removal of the monomers, as a two-dimensional master structure for the incorporation of biologically relevant lipid bilayer membranes.