Unique Regulation Profile of Prostaglandin E1 on Adhesion Molecule Expression and Cytokine Production in Human Peripheral Blood Mononuclear Cells

Cloning of a new cytokine that induces IFN-γ production by T cells

Haruki Okamura, Hiroko Tsutsui, Toshinori Komatsu et al. · Nature · 1995 · 2.6K citations

Immune Cell Development, Immunology, Immune Regulation +10

Prostacyclin Synthase Expression Is Decreased in Lungs from Patients with Severe Pulmonary Hypertension

Rubin M. Tuder, Carlyne D. Cool, MARK W. GERACI et al. · American Journal of Respiratory and Critical Care Medicine · 1999 · 791 citations

Hypertension, Inflammatory Lung Disease, Severe Pulmonary Hypertension +22

Altered pain perception and inflammatory response in mice lacking prostacyclin receptor

Fumitaka Ushikubi, Toshiyuki Matsuoka, Masakazu Hirata et al. · Nature · 1997 · 782 citations

Inflammation, Health Sciences, Acute Pain +12

Long-Term Treatment of Primary Pulmonary Hypertension with Aerosolized Iloprost, a Prostacyclin Analogue

Marius M. Hoeper, Michaël Schwarze, Stefan Ehlerding et al. · New England Journal of Medicine · 2000 · 573 citations · Full text

Prostaglandins posttranscriptionally inhibit monocyte expression of interleukin 1 activity by increasing intracellular cyclic adenosine monophosphate.

Peter Juel Thiis Knudsen, C A Dinarello, T B Strom · The Journal of Immunology · 1986 · 457 citations · Full text

Immunology, Immunologic Mechanism, Immunotherapy +19