Pharmacokinetics of Gemcitabine in Japanese Cancer Patients: The Impact of a Cytidine Deaminase Polymorphism - Concepedia

Concepedia

Publication | Closed Access

Pharmacokinetics of Gemcitabine in Japanese Cancer Patients: The Impact of a Cytidine Deaminase Polymorphism

187

Citations

35

References

2006

Year

Emiko Sugiyama, Nahoko Kaniwa, Su-Ryang Kim, Ruri Kikura‐Hanajiri, Ryuichi Hasegawa, Keiko Maekawa, Yoshiro Saito, Shogo Ozawa, Jun‐ichi Sawada, Naoyuki Kamatani,

Journal of Clinical Oncology

Abstract

Haplotype *3 harboring a nonsynonymous SNP, 208G>A (Ala70Thr), decreased clearance of gemcitabine, and increased incidences of neutropenia when patients were coadministered platinum-containing drugs or fluorouracil.

References

	Year	Citations

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