Effect of short‐ and long‐term treatment with omeprazole on the absorption and serum levels of cobalamin

Abstract

Absorption of protein-bound, but not unbound, cyanocobalamin is decreased when measured by a modified Schilling test during treatment with omeprazole. However, no change in serum cobalamin levels was observed in patients with GERD after treatment with omeprazole for up to 7 years.