Efflux Systems and Increased Trypanothione Levels in Arsenite-ResistantLeishmania

Antibodies, a laboratory manual

Biomedicine & Pharmacotherapy · 1989 · 12.5K citations

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The amplified H circle of methotrexate-resistant leishmania tarentolae contains a novel P-glycoprotein gene.

Marc Ouellette, F. Fase-Fowler, Piet Borst · The EMBO Journal · 1990 · 259 citations · Full text

Novel P-glycoprotein Gene, Biochemistry, Glycosylation +11

Drug Resistance in Leishmaniasis: Its Implication in Systemic Chemotherapy of Cutaneous and Mucocutaneous Disease

Max Grögl, T N Thomason, E D Franke · American Journal of Tropical Medicine and Hygiene · 1992 · 249 citations

Systemic Chemotherapy, Parasitic Disease, Antiparasitic Agent +13

Overproduction of a bifunctional thymidylate synthetase-dihydrofolate reductase and DNA amplification in methotrexate-resistant Leishmania tropica.

Jeffrey A. Coderre, Stephen M. Beverley, Robert Schimke et al. · Proceedings of the National Academy of Sciences · 1983 · 240 citations · Full text

Gene Amplification, Biosynthesis, Engineering +13

Trypanothione overproduction and resistance to antimonials and arsenicals in Leishmania.

Rita Mukhopadhyay, Saikat Dey, Ning Xu et al. · Proceedings of the National Academy of Sciences · 1996 · 235 citations · Full text

Biochemistry, Antiparasitic Agent, Drug Resistance +13