A Highly Stereoselective Hydrogen‐Bond‐Mediated Michael–Michael Cascade Process through Dynamic Kinetic Resolution

Abstract

Oh Mickey, you're so fine: The title reaction, which is efficiently catalyzed by a cinchona alkaloid thioure affords direct access to thiochromanes in high efficiency. The reaction features a new activation mode of organocatalytic dynamic kinetic resolution involving a Michael–retro-Michael–Michael–Michael cascade. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z800381_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.