A Highly Stereoselective Hydrogen‐Bond‐Mediated Michael–Michael Cascade Process through Dynamic Kinetic Resolution

Abstract

Oh Mickey, you're so fine: The title reaction, which is efficiently catalyzed by a cinchona alkaloid thioure affords direct access to thiochromanes in high efficiency. The reaction features a new activation mode of organocatalytic dynamic kinetic resolution involving a Michael–retro-Michael–Michael–Michael cascade.