Evaluation of antiulcer activity of Ocimum Sanctum in rats

Abstract

Aqueous extract of Ocimum sanctum was evaluated for its Antiulcer activity against methanol induced ulcer in Wistar rats. The aqueous extract ofOcimum sanctum at the dose rate of 100mg /kg an 200 mg/kg per orally exhibited significant protection against ethanol induced gastric ulceration. The present investigation revealed that Ocimum sanctum exhibited significant antiulcer activity by enhancing antioxidant potential of gastric mucosa thereby reducing mucosal damage. [Vet World 2009; 2(12.000): 465-466]