Application of orthogonal functions to spectrophotometric analysis. The combined polynomial method

Abstract

Abstract A general method is outlined for the linear combination of orthogonal polynomials belonging to one group of points to eliminate interferences in spectrophotometric analysis. The method is particularly useful when it is difficult to find a set of wavelengths over which the coefficient of the irrelevant absorption is negligibly small relative to the assay coefficient. The method is illustrated by the determination of salicylamide in the presence of chloroquine.