High levels of macrolide resistance-associated mutations in<i>Mycoplasma genitalium</i>warrant antibiotic susceptibility-guided treatment

Abstract

This study shows that macrolide resistance-associated mutations in M. genitalium occur with a high frequency. In contrast to studies from other regions, Dutch M. genitalium isolates carry the A2058T mutation at high frequency. Our data confirm the need for prospective detection of macrolide resistance-associated mutations prior to treating patients.