Optics Letters · 1991 · 166 citations · 21 references
Natural SciencesBiomedical EngineeringBiomedical ImagingDiagnostic ImagingOpticsImagingNonlinear Optical MicroscopyNonlinear OpticsOptical ImagingSuper-resolution MicroscopyUltrafast OpticsFemtosecond Laser PulsesHigh-harmonic GenerationMean Free PathMean Free Path AnalysisSecond-harmonic GenerationSecond-harmonic Generation MicroscopySecond-harmonic ImagingUltrafast Laser Excitation
A combination of 100-fs cross-correlation time gating and lock-in amplifier detection is shown to be a versatile technique to image objects hidden in highly scattering media. The image is formed from the ballistic component of the ultrafast laser pulse while the diffuse component is eliminated by time gating using cross-correlation second-harmonic generation. The low-noise lock-in amplifier detection method and the high-repetition-rate milliwatt pulsed laser enable us to image through a random medium as thick as 28 scattering mean free paths with submillimeter resolution.
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Time-resolved transillumination for medical diagnostics
Stefan Andersson‐Engels, O. Jarlman, Roger Berg et al. · Optics Letters · 1990 · 257 citations · Full text