Determination of optimal conditions for analysis of p53 status in leukemic cells using functional analysis of separated alleles in yeast

Suppression of Human Colorectal Carcinoma Cell Growth by Wild-Type p53

Suzanne J. Baker, Sanford D. Markowitz, Eric R. Fearon et al. · Science · 1990 · 1.8K citations

Medicine, Genetics, Oncology +17

Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents.

P M O'Connor, Joany Jackman, I Bae et al. · PubMed · 1997 · 882 citations

Medicine, Cancer Biology, Molecular Biology +15

A simple p53 functional assay for screening cell lines, blood, and tumors.

Jean‐Michel Flaman, Thierry Frébourg, Viviane Moreau et al. · Proceedings of the National Academy of Sciences · 1995 · 451 citations

Life Sciences, Molecular Biology, Molecular Genetics +13

The p53 Gene in Breast Cancer: Prognostic Value of Complementary DNA Sequencing Versus Immunohistochemistry

S. Sjögren, Mats Inganäs, Torbjörn Norberg et al. · JNCI Journal of the National Cancer Institute · 1996 · 388 citations · Full text

Medicine, Molecular Biology, Oncology +16

Screening patients for heterozygous p53 mutations using a functional assay in yeast

Chikashi Ishioka, Thierry Frébourg, Yu-Xin Yan et al. · Nature Genetics · 1993 · 238 citations

Life Sciences, Genetics, Molecular Genetics +14