Effect of combining dexmedetomidine and morphine for intravenous patient-controlled analgesia

The Effects of Increasing Plasma Concentrations of Dexmedetomidine in Humans

Thomas J. Ebert, Judith Hall, Jill A. Barney et al. · Anesthesiology · 2000 · 1.4K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +12

Substitution of a mutant α _2a -adrenergic receptor via “hit and run” gene targeting reveals the role of this subtype in sedative, analgesic, and anesthetic-sparing responses <i>in vivo</i>

Parul P. Lakhlani, Leigh B. MacMillan, Tian Z. Guo et al. · Proceedings of the National Academy of Sciences · 1997 · 366 citations · Full text

Medicine, Neuroscience, Pharmacology +17

The Efficacy of Dexmedetomidine Versus Morphine for Postoperative Analgesia After Major Inpatient Surgery

Shahbaz R. Arain, Ren e M. Ruehlow, Toni D. Uhrich et al. · Anesthesia & Analgesia · 2004 · 364 citations

Medicine, Anesthesiology, Surgery +17

Pharmacokinetics of dexmedetomidine infusions for sedation of postoperative patients requiring intensive care †

R.M. Venn, Michael D. Karol, RM Grounds · British Journal of Anaesthesia · 2002 · 240 citations

Medicine, Anesthesiology, Pharmacokinetics +14

Antinociceptive interactions between alpha 2-adrenergic and opiate agonists at the spinal level in rodents.

Michael H. Ossipov, Linda J. Suarez, Theodore C. Spaulding · PubMed · 1989 · 197 citations

Medicine, Pharmacology, Neuropharmacology +16