Durable Pharmacological Responses from the Peptide ShK-186, a Specific Kv1.3 Channel Inhibitor That Suppresses T Cell Mediators of Autoimmune Disease

Design of a potent and selective inhibitor of the intermediate-conductance Ca ²⁺ -activated K ⁺ channel, <i>IKCa1</i> : A potential immunosuppressant

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Medicine, Medicinal Chemistry, Pharmacology +13

Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases

Christine Beeton, Heike Wulff, Nathan Standifer et al. · Proceedings of the National Academy of Sciences · 2006 · 538 citations

Life Sciences, Cell Biology, Immunology +17

The voltage-gated Kv1.3 K+ channel in effector memory T cells as new target for MS

Heike Wulff, Peter A. Calabresi, Rameeza Allie et al. · Journal of Clinical Investigation · 2003 · 418 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Selective blockade of T lymphocyte K ⁺ channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis

Christine Beeton, Heike Wulff, Jocelyne Barbaria et al. · Proceedings of the National Academy of Sciences · 2001 · 318 citations · Full text

Life Sciences, Immunology, Neurology +17

Receptor-mediated radionuclide therapy with 90Y-DOTATOC in association with amino acid infusion: a phase I study

Lisa Bodei, Marta Cremonesi, Stefania Zoboli et al. · European Journal of Nuclear Medicine and Molecular Imaging · 2003 · 305 citations

Medicine, Nuclear Medicine, Pharmacology +14