A Key Role for Diacylglycerol Lipase-α in Metabotropic Glutamate Receptor-Dependent Endocannabinoid Mobilization

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

Raphael Mechoulam, Shimon Ben‐Shabat, L Hanŭs et al. · Biochemical Pharmacology · 1995 · 2.9K citations

Life Sciences, Pharmacology, Veterinary Pharmacology +10

2-Arachidonoylgylcerol: A Possible Endogenous Cannabinoid Receptor Ligand in Brain

Takayuki Sugiura, Shigeru Kondo, Akihiro Sukagawa et al. · Biochemical and Biophysical Research Communications · 1995 · 2.2K citations

Medicine, Neuroscience, Pharmacology +9

A second endogenous cannabinoid that modulates long-term potentiation

Nephi Stella, Paul Schweitzer, Daniele Piomelli · Nature · 1997 · 1.5K citations · Full text

Medicine, Neuroscience, Pharmacology +13

Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

Thomas Hofmann, Alexander G. Obukhov, Michael Schaefer et al. · Nature · 1999 · 1.5K citations

Life Sciences, Pharmacology, Physiology +16

Brain monoglyceride lipase participating in endocannabinoid inactivation

T. P. Dinh, D. L. Carpenter, F.M. Leslie et al. · Proceedings of the National Academy of Sciences · 2002 · 1.4K citations · Full text

Life Sciences, Neurobiology, Neuroscience +15