Helvetica Chimica Acta · 1969 · 25 citations · 4 references
PharmacyBotanyPlant SciencesDrug DiscoveryPlant BiochemistrySynthetic Medicinal ChemistryAlkaloid BiosynthesisMedicinal Plant KnowledgeMedicinal PlantsNatural Product Drug DiscoveryAlkaloid ReductionPlant Alkaloids
Abstract The alkaloids akuammiline ( 1 ) and anhydrovobasindiol ( 6 ) were isolated from the trunk bark of the Apocynacea Conopharyngia durissima S TAPF . The structure of the unknown base anhydrovobasindiol was elucidated and this base was partially synthetised from the alkaloid vobasine. The well‐known akuammiline could be correlated by LiAlH 4 reduction to picralinol ( 4 ).
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