Distribution of misonidazole in human tumours and normal tissues

Clinical testing of the radiosensitiser Ro-07-0582 I. dose tolerance, serum and tumour concentrations

Alan Gray, Stanley Dische, G.E. Adams et al. · Clinical Radiology · 1976 · 124 citations

Medicine, Oncology, Radiation Oncology +16

Clinical Phase I Study of the Hypoxic Cell Radiosensitizer RO-07-0582, A 2-Nitroimidazole Derivative

Raul C. Urtasun, Pierre R. Band, JD Chapman et al. · Radiology · 1977 · 116 citations

Pharmacy, Oncology, Pharmacology +16

Estimation of the hypoxic cell-sensitiser misonidazole and its O-demethylated metabolite in biological materials by reversed-phase high-performance liquid chromatography

Paul Workman, C.J. Little, T. R. Marten et al. · Journal of Chromatography B Biomedical Sciences and Applications · 1978 · 93 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Radiosensitization by Misonidazole (Ro 07-0582) The Importance of Timing and Tumor Concentration of Sensitizer

Nicolas J. McNally, J. Denekamp, P.W. Sheldon et al. · Radiation Research · 1978 · 59 citations

Medicine, Oncology, Pharmacology +14

Distribution and tumour cytotoxicity of the radiosensitizer misonidazole (Ro-07-0582) in C57 mice

J.E. Pedersen, Mitchell R. Smith, R D Bugden et al. · British Journal of Cancer · 1979 · 29 citations · Full text

Medicine, Oncology, Pharmacology +13