Synthesis and in vitro antibacterial activity of gemifloxacin derivatives containing a substituted benzyloxime moiety

Gyrase inhibitors induce an oxidative damage cellular death pathway in <i>Escherichia coli</i>

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Mechanism of inhibition of DNA gyrase by quinolone antibacterials: a cooperative drug-DNA binding model

Linus L. Shen, Lester A. Mitscher, Padam N. Sharma et al. · Biochemistry · 1989 · 416 citations

Molecular Biology, Specific Quinolone, Antimicrobial Chemotherapy +20

Synthesis and antibacterial activity of N-(5-benzylthio-1,3,4-thiadiazol-2-yl) and N-(5-benzylsulfonyl-1,3,4-thiadiazol-2-yl)piperazinyl quinolone derivatives

Alireza Foroumadi, Saeed Emami, Abdolreza Hassanzadeh et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 139 citations

Bioorganic Chemistry, Antibacterial Activity, Organic Chemistry +6

Novel Fluoroquinolone Antibacterial Agents Containing Oxime-Substituted (Aminomethyl)pyrrolidines:  Synthesis and Antibacterial Activity of 7-(4-(Aminomethyl)-3-(methoxyimino)pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro- 4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxylic Acid (LB20304)^,1

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Bioorganic Chemistry, Antibacterial Activity, Organic Chemistry +17

Synthesis, antibacterial and antitubercular activities of some 7-[4-(5-amino-[1,3,4]thiadiazole-2-sulfonyl)-piperazin-1-yl] fluoroquinolonic derivatives

Sirajunisa Talath, Andanappa K. Gadad · European Journal of Medicinal Chemistry · 2006 · 117 citations

Medicinal Chemistry, Pharmaceutical Chemistry, Natural Sciences +8