Concepedia

Hepatic Veno-Occlusive Disease Associated with Immunosuppressive Cyclophosphamide Dosing and Roxithromycin

Johannes Beltinger, Manuel Haschke, Priska Kaufmann, Marc Michot, Luigi Terracciano, Stephan Krähenbühl

Annals of Pharmacotherapy · 2006 · 12 citations · 8 references

DOI

Abstract

In specific patients, cyclophosphamide can be associated with hepatic veno-occlusive disease at immunosuppressive doses.

References

8

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C. A. Naranjo, U. Busto, Edward M. Sellers et al. · Clinical Pharmacology & Therapeutics · 1981 · 11.4K citations

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Thrombospondin-1 Associated with Tumor Microenvironment Contributes to Low-Dose Cyclophosphamide-Mediated Endothelial Cell Apoptosis and Tumor Growth Suppression

Yuki Hamano, Hikaru Sugimoto, Mary A. Soubasakos et al. · Cancer Research · 2004 · 187 citations · Full text

Comparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6beta-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin.

Hiroshi Yamazaki, Tsutomu Shimada · PubMed · 1998 · 64 citations

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Characterization of the cytochrome P450 involved in side-chain oxidation of cyclophosphamide in humans

Frank Bohnenstengel, Ute Hofmann, Michel Eichelbaum et al. · European Journal of Clinical Pharmacology · 1996 · 48 citations

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Toxicity, uptake, and subcellular distribution in rat hepatocytes of roxithromycin, a new semisynthetic macrolide, and erythromycin base

Pia Villa, D Sassella, Monica Corada et al. · Antimicrobial Agents and Chemotherapy · 1988 · 28 citations · Full text

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