Potential Peptide Carriers: Amphipathic Proline‐Rich Peptides Derived from the N‐Terminal Domain of γ‐Zein

Abstract

Breaking into cells: A new family of peptides based on the amphipathic proline-rich sequence (VXLPPP)n, where n=1–3 and X=His, Lys, or Arg, has been designed (see picture). Their nonviral origin, absence of toxicity at high concentrations, and high solubility in water make this new series very promising for use in drug delivery.