Ubiquitin‐specific protease 7 accelerates p14ARF degradation by deubiquitinating thyroid hormone receptor‐interacting protein 12 and promotes hepatocellular carcinoma progression - Concepedia

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Ubiquitin‐specific protease 7 accelerates p14ARF degradation by deubiquitinating thyroid hormone receptor‐interacting protein 12 and promotes hepatocellular carcinoma progression

123

Citations

29

References

2014

Year

Jiabin Cai, Guo‐Ming Shi, Zhao‐Ru Dong, Ai‐Wu Ke, Honghui Ma, Qiang Gao, Zao‐Zhuo Shen, Xiaoyong Huang, Hao Chen, Dingdang Yu,

Abstract

USP7 stabilizes TRIP12 by deubiquitination, thus constitutively inactivating p14(ARF) and promoting HCC progression. This represents a novel marker for predicting prognosis and a potential therapeutic target for HCC.

References

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