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One-Pot Primary Aminomethylation of Aryl and Heteroaryl Halides with Sodium Phthalimidomethyltrifluoroborate
36
Citations
31
References
2012
Year
Suzuki–miyaura Cross-coupling ReactionsCross-coupling ReactionHeteroaryl HalidesEngineeringAlkene MetathesisFluorous SynthesisOne-pot Primary AminomethylationOrganic ChemistryStereoselective SynthesisChemistrySodium PhthalimidomethyltrifluoroborateHeterocycle ChemistryHalogenationBiomolecular Engineering
A one-pot primary aminomethylation of aryl halides, triflates, mesylates, and tosylates via Suzuki–Miyaura cross-coupling reactions with sodium phthalimidomethyltrifluoroborate followed by deamidation with ethylenediamine is reported.
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