Antisense RNA Down-Regulation of bcl-2 Expression in DU145 Prostate Cancer Cells Does Not Diminish the Cytostatic Effects of G3139 (Oblimersen) - Concepedia

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Antisense RNA Down-Regulation of bcl-2 Expression in DU145 Prostate Cancer Cells Does Not Diminish the Cytostatic Effects of G3139 (Oblimersen)

47

Citations

28

References

2004

Year

Anthony J. Raffo, Johnathan C. Lai, C.A. Stein, Paul S. Miller, Steven Scaringe, Anastasia Khvorova, Luba Benimetskaya

Clinical Cancer Research

Abstract

These results strongly suggest that bcl-2 expression in DU145 cells is not strongly associated with the prolife phenotype and that the mechanism by which G3139 produces its cytostatic effects in this cell line is bcl-2 independent.

References

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