Remote Chiral Induction in the Organocatalytic Hydrosilylation of Aromatic Ketones and Ketimines

Abstract

Lewis basic, metal-free pyridyloxazolines catalyze the reduction of prochiral aromatic ketones and ketimines with Cl3SiH in good enantioselectivity (up to 94 % ee). Arene–arene interactions between the substrate and the catalyst are likely to play a role in the enantiodifferentiation process. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2006/z503941_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.