Serum concentration of interleukin 10, anti-mannan Candida antibodies and the fungal colonization of the gastrointestinal tract in patients with ulcerative colitis

Interleukin-10-deficient mice develop chronic enterocolitis

Ralf Kühn, Jürgen Löhler, D Rennick et al. · Cell · 1993 · 4.3K citations

Inflammation, Cytokine, Autoimmune Disease +6

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

René de Waal Malefyt, J S Abrams, B Bennett et al. · The Journal of Experimental Medicine · 1991 · 3.8K citations · Full text

Immunology, Immune Regulation, Immunologic Mechanism +19

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.

David Fiorentino, M W Bond, Timothy R. Mosmann · The Journal of Experimental Medicine · 1989 · 2.7K citations

Th2 Clones, Adaptive Immune System, T-regulatory Cell +20

Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)

Rainer Duchmann, I Kaiser, E Hermann et al. · Clinical & Experimental Immunology · 1995 · 948 citations · Full text

Immunoregulatory role of interleukin 10 in patients with inflammatory bowel disease

Stefan Schreiber, Thomas Heinig, H Thiele et al. · Gastroenterology · 1995 · 374 citations

Inflammation, Chronic Inflammatory Diseases, Cytokine +11