Capillary electrochromatography/mass spectrometry: Principles and potential for application in the pharmaceutical industry

Abstract

Abstract Capillary electrochromatography (CEC) was coupled with electrospray (ESI) mass spectrometry and evaluated as an on‐line high resolution technique for the separation and characterization of some typical pharmaceutical compound mixtures. Dispersion effects were observed and are discussed in the context of an optimized CEC/MS interface.