Concepedia

Chemical Synthesis of Polynucleotides

K Agarwal, Akira Yamazaki, Peter Cashion, H. G. Khorana

Angewandte Chemie International Edition in English · 1972 · 104 citations · 21 references

DOI

Concepts

Abstract

Abstract Current methodology for the chemical synthesis of short chains (up to about twenty nucleotide units) of deoxyribopolynucleotides is reviewed.

References

21

Nucleoside Polyphosphates. X.<sup>1</sup> The Synthesis and Some Reactions of Nucleoside-5' Phosphoromorpholidates and Related Compounds. Improved Methods for the Preparation of Nucleoside-5' Polyphosphates<sup>1</sup>

J. G. Moffatt, H. G. Khorana · Journal of the American Chemical Society · 1961 · 473 citations

, , +6

<b>Studies on Polynucleotides. XXIV.</b><sup>1</sup> <b>The Stepwise Synthesis of Specific Deoxyribopolynucleotides (4).</b><sup>2</sup> <b>Protected Derivatives of Deoxyribonucleosides and New Syntheses of Deoxyribonucleoside-3″ Phosphates</b><sup>3</sup>

Heinz Schaller, G. Weimann, B. Lerch et al. · Journal of the American Chemical Society · 1963 · 402 citations

, , +7

The Total Synthesis of Cephalosporin C<sup>1</sup>

R. B. Woodward, K. Heusler, J. Gosteli et al. · Journal of the American Chemical Society · 1966 · 357 citations

, , +6

Total Synthesis of the Gene for an Alanine Transfer Ribonucleic Acid from Yeast  

K Agarwal, H. Büchi, Marvin H. Caruthers et al. · Nature · 1970 · 273 citations

, , +12

Oligonucleotide Synthesis on a Polymer Support<sup>1,2</sup>

Robert L. Letsinger, V. Mahadevan · Journal of the American Chemical Society · 1965 · 203 citations

, , +6